Baby or Your Money Back planA fertility treatment programme that promises a baby or your money back has been taken up by 11 couples since its launch in April and is attracting interest from Australian clinics.

The Fertility Associates option was launched in Wellington and has been rolled out in Auckland and Hamilton. It was designed to insure eligible patients against the soaring costs of in-vitro fertilisation (IVF).

Fertility Cover offers three cycles of IVF for a fixed price and, if the treatment is unsuccessful, patients receive a 70 percent refund. A single cycle of private IVF can cost $10,000 to $15,000 and about half the patients conceive.

About 80 percent of Fertility Associates patients succeed after three cycles. Fertility Cover offers a three- cycle package for eligible women under 39 at $24,000 or $30,000, depending on age.

Read more: http://www.stuff.co.nz/life-style/2815446/Interest-in-baby-or-your-money-back-plan

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What is the Conception Kit?
The Conception Kit™ is designed for couples who want to enhance their opportunity to conceive in the privacy of home.

Each kit contains the only FDA-cleared cervical cap for at-home conception, fertility prediction tools, semen collectors, pregnancy tests and timing wheels. These components are designed to be used together for up to three months.

How does it work? The cornerstone of the kit is the Conception Cap®, which brings the semen in direct contact with the opening of the cervix for four to six hours. This allows the sperm cells a greater opportunity to move into the uterine cavity and fertilize an egg.

The Conception Kit™ is a three-month supply and is now covered by many health insurance plans for a simple co-pay of $25-$50. Click here for details on insurance coverage.

The Conception Kit™ is available by prescription only in the United States. A free prescription may be obtained by filling out a brief medical history form during the on-line checkout process.

Read more: http://www.conceptionkit.com

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Barad D.H., Gleicher N. Increased oocyte production after treatment with dehydroepiandrosterone (2005) Fertility and Sterility, 84 (3), pp. 756.e1-756.e3.
Abstract Objective: To describe a case of dramatically improved ovarian reserve in a 42.7-year-old woman who was using the dietary supplement dehydroepiandrosterone (DHEA) as well as acupuncture.

Setting: Private IVF center.

Patient(s): A 42.7-year-old patient with initial severely decreased ovarian reserve. Intervention(s): Serial ovulation induction with concomitant use of DHEA dietary supplementation as well as acupuncture.

Main Outcome Measure(s): Peak E2 concentration, oocytes retrieved, and cyropreservable embryos. Result(s): In her first treatment cycle peak E 2 was 1,211 pmol/mL. After seven months of DHEA supplementation her peak E2 in cycle 8 was >18,000 pmol/mL. Because of fear of hyperstimulation we reduced her gonadotropin stimulation by 25%. In the ninth cycle peak E2 was 9,178 pmol/mL, resulting in retrieval of 17 oocytes (16 embryos). In the last 11 months the patient has undergone nine treatment cycles while continuously and dramatically improving her ovarian response and banking of 66 embryos overall.

Conclusion(s): This case illustrates the possibility that ovarian function may be salvaged, even in women of advanced reproductive age.
©2005 by American Society for Reproductive Medicine.

Barad D., Gleicher N. Effect of dehydroepiandrosterone on oocyte and embryo yields, embryo grade and cell number in IVF (2006) Human Reproduction, 21 (11), pp. 2845-2849.

Abstract Background: The aim of this study was to investigate the effect of treatment with dehydroepiandrosterone (DHEA) on fertility outcomes among women with diminished ovarian reserve.

Materials and Methods: This is a case-control study in an academically affiliated private infertility centre. Twenty-five women with significantly diminished ovarian reserve had one IVF cycle before and after DHEA treatment, with otherwise identical hormonal stimulation. Women received 75 mg of DHEA daily (25 mg three times daily) for an average of 17.6 ± 2.13 weeks. We performed a comparison of IVF outcome parameters, before and after DHEA treatment, including peak estradiol (E2) levels, oocyte and embryo numbers, oocyte and embryo quality and embryo transfer statistics.

Results: Paired analysis of IVF cycle outcomes in 25 patients, who underwent cycles both before and after DHEA supplementation, demonstrated significant increases in fertilized oocytes (P < p =" 0.001)," p =" 0.005)">

Conclusion: This study confirms the previously reported beneficial effects of DHEA supplementation on ovarian function in women with diminished ovarian reserve.
© 2006 Oxford University Press.

Barad D., Brill H., Gleicher N. Update on the use of dehydroepiandrosterone supplementation among women with diminished ovarian function (2007) Journal of Assisted Reproduction and Genetics, 24 (12), pp. 629-634.

Abstract Objective: We assessed the role of DHEA supplementation on pregnancy rates in women with diminished ovarian function.

Design: This is a case control study of 190 women with diminished ovarian function. The study group includes 89 patients who used supplementation with 75 mg daily of oral, micronized DHEA for up to 4 months prior to entry into in vitro fertilization (IVF). The control group is composed of 101 couples who received infertility treatment, but did not use DHEA. The primary outcome was clinical pregnancy after the patient's initial visit. We developed a Cox proportional hazards model to compare the proportional hazards of pregnancy among women using DHEA with the controls group.

Results: Cumulative clinical pregnancy rates were significantly higher in the study group (25 pregnancies; 28.4% vs. 11 pregnancies; 11.9%; relative hazard of pregnancy in study group (HR 3.8; 95% CI 1.2-11.8; p<0.05).>Conclusions: DHEA treatment resulted in significantly higher cumulative pregnancy rates. These data support a beneficial effect of DHEA supplementation among women with diminished ovarian function.
© 2007 Springer Science+Business Media, LLC.

Fernandez-Shaw S., Ruesta C., Cercas R., Pons I. Use of dehydroepiandrosterone (DHEA) in low responders [Uso de dehydroepiandrosterone (DHEA) en bajas respondedoras] (2008) Revista Iberoamericana de Fertilidad y Reproduccion Humana, 25 (4), pp. 233-238.

Abstract Objective: To compare results in IVF cycles from patients with ovarian failure before and after treatment with Dehydroepiandrosterone (DHEA). Method: We included 16 patients with ovarian failure and a previous IVF cycle with a very low response. Ovarian stimulation was carried out following short protocols with recombinant FSH. We compared paired IVF results from women before and after treatment with DHEA (75 mg for 4 months).

Results: Basal FSH and estradiol were the same before and treatment with DHEA. Treatment with DHEA lowered the number of cancelled cycles and increased, although not significantly, the number of growing follicles, retrieved oocytes, mature oocytes, embryos and pregnancies obtained. Out of the 16 patients enrolled, one got pregnant spontaneously after two months of treatment with DHEA, 4 abandoned the study and 11 performed a cycle of IVF after treatment with DHEA.

Conclusion: Exogenous DHEA might be a concomitant treatment to offer to low responders to improve their ovarian stimulation, increasing the number of patients that achieve embryo transfer, and improving therefore their chances of pregnancy. However, success of this treatment is moderate, since patients, even after treatment with DHEA, continue to be low responders.


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Beaverton, Ore. -- U.S. researchers say they have used implanted donor eggs to prevent the inheritance of a class of mitochondrial disorders in non-human primates.

Scientists at the Oregon Health Science University in Beaverton, Ore., said they transferred hereditary material from the egg of a primate mother into a donor female's egg from which the hereditary material had been emptied. The resulting eggs were fertilized with donor sperm and implanted in the mothers, producing offspring having mitochondria only from the donated egg.

Read more: http://www.themoneytimes.com/20090826/new-method-may-prevent-disease-inheritance-id-1081514.html

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Found on Fertility Friend today:

Extract from: Canadian Consensus on Menopause and Osteoporosis (Update Sept 12, 2002)
RECOMMENDATIONS:
A2 Healthcare providers should not use random serum markers of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol E2 for the purpose of predicting menopause since clear markers for predicting menopause are yet to be identified. (II-2)

I'm shocked because I went to the doctor and he did a blood test called FSH which showed I'm menopausal even though I'm having regular periods. How can this be?

Hormonal blood tests are notoriously unreliable as hormone levels vary widely from day to day and even during the day. The FSH test is basically useless for determining what stage of the perimenopausal transition anybody is in. Here are statements from the abstracts of three studies you can find on Medline. You might like to print out the whole abstracts and show them to your doctor if you want to convince him. Of course he *could* simply mean "perimenopausal" - the two words are often used interchangeably (and confusingly!)

http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6790204&form=6&db=m&Dopt=b
Clin Endocrinol (Oxf) 1981 Mar;14(3):245-255

Pituitary-ovarian function in normal women during the menopausal transition.

It is concluded that the appearance of high levels of FSH and LH is characteristic of the perimenopause and often precedes the sustained loss of sex hormone secretion by the ageing ovary. Postmenopausal biochemical parameters are no guarantee of the postmenopausal state.
________________________________________
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8107620&form=6&db=m&Dopt=b
Maturitas 1993 Dec;18(1):9-20

Perimenopausal patterns of gonadotrophins, immunoreactive inhibin, oestradiol and progesterone.

It was concluded that typical postmenopausal hormone patterns may occur at the time of entry into the normal menopausal transition, and in some women with anovulatory infertility, but may be completely and relatively abruptly reversible. Elevation of serum FSH into the postmenopausal range, with undetectable INH concentrations, does not provide reliable evidence that the menopause (or permanent ovarian failure) has occurred. INH contributes to elevations of serum FSH during the menopausal transition.
________________________________________
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8124478&form=6&db=m&Dopt=b
Eur J Endocrinol 1994 Jan;130(1):38-42

Diagnostic role of follicle-stimulating hormone (FSH) measurements during the menopausal transition--an analysis of FSH, oestradiol and inhibin.

It is concluded that FSH measurement is of little value, if any in the assessment of women during the menopausal transition because it cannot be interpreted reliably and because, apparently, ovulatory (and, presumably, potentially fertile) cycles may occur subsequent to the observation of postmenopausal FSH levels. Both oestradiol and inhibin are important negative feedback regulators of circulating FSH.
________________________________________
extract from Menopause 1999;6:29¬35. © 1999, The North American Menopause Society
http://www.menopause.org/abstract/6129.htm

Among U.S. women aged 35¬60 years, median FSH and LH levels began to increase for women in their late 40s and reached a plateau for women in their early 50s.This study supports the previously reported association between serum FSH and age (i.e., serum FSH and LH levels increase with age) and smoking (i.e., current smoking was associated with an increased level of serum FSH). At FSH levels of = or >15 IU/L or = or >20 IU/L, 70 and 73% of women, respectively, were postmenopausal. Our study also found an interaction between age and oophorectomy. In addition, the present data suggest that women with only one ovary may have higher FSH levels than women with both of their ovaries.
________________________________________
From: Gail Gillespie

This discussion of the FSH test took me back to my menopausal transition, reminding me of some of the more horrifying absurdities foisted on me by the medicalization of menopause. For example, when, at 48, heavy bleeding drove me to the doctor's office, I was given the test - as part of a general check up to see what was going on, or so I thought. When the results came back the doctor told me that they would have to perform an endometrial biopsy to "check for cancer" since my FSH was "similar to a 29 year old's." Great.

So, then, after the (very painful for me) endo. biopsy showed nothing abnormal, they put me on ever-increasing doses of provera to curtail the bleeding - which paradoxically increased to the pointt where I had a 70 day continuous bleed accompanied by cramps just this side of childbirth. Weak from exhaustion/anemia, I dragged myself in again to the same doctor who then gave me a second FSH test. (The fact that I was taking 20 mg of provera a day seemed immaterial to him!)

Studying the new FSH results, he then told me that because of my unexplained POSTmenopausal bleeding I would require a more-or-less immediate hysterectomy. I should sign up right then and there because he was "very busy" in October.

When I reacted with shock, since the biopsy, which was normal, was also based on the FSH results which suggested a NON post-meno. status, the doctor became very condescending. He indicated that this second blood test indicated that my FSH had gone from 9 to 51 (in a couple of months) and suggested that I was now, suddenly, POST menopausal. Then he began to hint darkly at the possibility that I may have cancer or at least fibroids because POST menopausal bleeding is one of the major signals of serious trouble. As angry as it makes me to recount this, it also strikes me that the fact that the doctor was an insensitive jerk helped in the long run since my distrust prompted me to check out things on my own.

Fortunately, by this time, I'd discovered alt.support.menopause and was reading Susan Love's book as well as a number of books on hysterectomy, including Cutler's. Looking back and checking my "bleeding journal," the entire situation reminds me eerily of childbirth, in which case, the fetal monitor, like the FSH test, is often the excuse for rampant, unnecessary intervention in a normal physiological process....an intervention which may, in the end, have dire consequences (such as the loss of perfectly healthy body parts). Incidentally, this doctor's remark to me when I fired him to get a second opinion, was "don't come crying to me when you get ovarian cancer."
-g
PS. To the newbies: I am doing just fine now. I feel better than I have since my 30s and have not bled for two years. I take no drugs other than the occasional ibuprofen and a multi-vitamin when I think about it. My only "symptoms" (hate that word) were a few hot flashes for several months as I made the adjustment to a drug free state. After what I went through, it was hard to go back to a doctor regularly though I do reluctantly get an annual PAP and mammogram.
________________________________________

So what are "normal" levels for FSH?
Note the wide range and overlap -
http://www.drkoop.com/adam/peds/top/003710.htm#Normal values
Normal values:
male: 4 to 25 U/L
female:
premenopausal: 4 to 30 U/L
midcycle peak: 10 to 90 U/L
pregnancy: low to undetectable
postmenopausal: 40 to 250 U/L
Note: U/L = units per liter
________________________________________


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Is In Vitro Fertilization Being Overused?(CBS) A pioneer of in vitro fertilization says the procedure is being overused, and that nearly half of all procedures are unnecessary. In his new book, "Making Babies: A Proven 3-Month Program for Maximum Fertility", Dr. Sami David takes the billion-dollar business to task.

Dr. David stopped by The Early Show to explain.

"The IVF team has gone amok as far as I'm concerned, all right? There are countless women who are going through IVF unnecessarily. They don't realize they're treatable causes for their infertility. They're not having a deep enough evaluation in many cases," he explained.

Read more: http://www.cbsnews.com/stories/2009/08/12/earlyshow/health/main5236035.shtml

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Discover Effective Ways to Cope with the Stress, Anxiety, and Grief of InfertilityThe journey of infertility can be incredibly stressful, often taking a toll on finances, relationships and peace of mind. Sometimes it's hard to know what to do to feel better.

Do not lose hope! There are effective ways to ease the path through this challenging time. Attend this Teleseminar to learn about typical reactions to an infertility diagnosis and ten powerful ways to protect yourself and your relationships during treatment.

A Teleseminar can be attended from the privacy and convenience of your own home or office. When you register online, you will be given a phone number to call at the presentation time to participate in the seminar.

TIME: Wednesday 8/26/09, 8:00 PM TO 9:00 PM Central Standard Time

COST: $29.95

REGISTRATION
Register at http://www.FertilityCounseling.com

Read more: http://www.prweb.com/releases/2009/08/prweb2754194.htm

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Following is a case of a 42-year-old man Mr. Narayanmurthy (name changed), who was suffering from Oligospermia. He had previously consulted many specialists but none of their treatments had shown any results.

Discouraged and depressed, he stopped the treatment and stopped socializing as well. After 6 years, Mr. Narayanmurthy, at a friend’s suggestion, visited Dr. Batra’s® Clinic. The doctor at the clinic reviewed his case after taking a detailed history, examining the patient and evaluating his reports. Read more: http://www.webnewswire.com/node/465127

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Correction: Sleep-deprivation linked to infertility. (I had a feeling that would get your attention.) Did you ever consider that? How could you with all the other things to worry about:

You've cut down on alcohol, caffeine, and even processed food.

You've scheduled more time to relax and tried to reduce the stress in your life.

You've started a consistent exercise routine and detoxified your house.

You've charted your monthly cycle, bought ovulation kits, and still...nothing.

But you've overlooked one very important element: sleep, which you don't get enough of.

Read more: http://www.huffingtonpost.com/dr-michael-j-breus/sleep-linked-to-infertili_b_260367.html

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Five Fertility Myths DebunkedMyth #1: If my period is regular, I’m fertile.

Myth #2: If I take good care of my general health, my fertility will be in check too.

Myth #3: If I’ve already had a baby, I won’t have problems conceiving again.

Myth #4: Infertility is primarily a woman’s issue.

Myth #5: 40 is the new 30; and that pertains to fertility too.

Read more: http://www.empowher.com/news/herarticle/2009/08/14/five-fertility-myths-debunked


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Belgian day-old baby Tamara Bouanati nestles in the arms of her mother Ouarda Touirat, 32. Touirat beat cancer and gave birth after an ovarian tissue transplant.A Belgian woman has given birth to the first baby born after an ovarian tissue transplant, a medical advance that gives hope to young cancer patients whose fertility may be damaged by chemotherapy.

The baby, a healthy girl named Tamara, was born at 7:05 p.m. on Thursday in a hospital in Brussels and weighed 8.2 lb. Her mother is Ouarda Touirat, 32, a hospital spokeswoman said.

Read more: http://www.msnbc.msn.com/id/6089202


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47-YEAR-OLD Melbourne woman has had radical surgery that may make her a first-time mother - and part of medical historyA 47-YEAR-OLD Melbourne woman has had radical surgery that may make her a first-time mother - and part of medical history.

Eight years after having "slices" of her ovaries removed, frozen and stored, Lisa had them reimplanted last month in the hope of becoming pregnant.

Specialists at Monash IVF hope the slices will regenerate in her reproductive system - and effectively reverse menopause by starting a process that will release eggs and make her fertile again.

If it works, Lisa could become the first woman in Australia to become pregnant using the technique.

Read more: http://www.news.com.au/heraldsun/story/0,21985,25934496-661,00.html


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Resolving the Loss of FertilityOne of the questions prospective parents are routinely asked during their adoption home study is whether they have "resolved" their infertility. This issue is raised because it is a widespread paradigm in the professional adoption community that infertile, prospective adoptive parents need to resolve their feelings of loss to fully accept their children.

Issues related to infertility that may impact adoptive families include loss of a "dream" or idealized child, loss of physical connection of pregnancy and biological heredity, and loss of continuity of inheritance. Resolution of these issues and feelings is intended to ensure that lingering frustration, anger, sadness or other emotions don't create tension or avoidance of important issues within the adoptive family.

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I Used an Egg DonorIn every fertility book I've read—and I've read plenty—there's a final chapter called "Other Paths to Parenthood" or "There's More Than One Road to Motherhood" or something similar.

These chapters talk about egg donation and adoption, about grieving the loss of your fertility and accepting a different path. When you're starting fertility treatment, these are the chapters you avoid. You think they're for other people — women who began trying to conceive at age 42 (Hey, what did they expect?) or who lost an ovary to cancer (Unfortunate, but at least they have options).

You suspect it would be awful to be in their shoes, but you barely give the scenario a passing thought. Given all the high-tech procedures you've heard of — IVF, ICSI, PGD — you're confident that something will work for you. Maybe not on the first try, but eventually.

Read more: http://www.fitpregnancy.com/yourpregnancy/fertility_conception/i-used-an-egg-donor-40722747.html


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A fertility company launched a revolutionary new deal for couples trying to conceive today - pregnancy in 12 months or your money back. The new £495 device promises to show women with 99 per cent accuracy when they are at their most fertile.

As part of the package, the couple are also promised unlimited support and advice from the company's fertility experts. Cambridge Temperature Concepts Ltd (CTC) hope the bizarre promotion will tempt hopeful couples into buying their DuoFertility ovulation detector. CTC, a company set up by Cambridge University PhD students in 2008, are so confident of success they will refund anyone who does not fall pregnant within a year. Offer expires on September 20

Read more:
http://www.chinadaily.com.cn/life/2009-08/10/content_8550108.htm

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If I cut out alcohol and caffeine will I really have as much chance of conceiving as if I try IVFQUESTION: If I cut out alcohol and caffeine will I really have as much chance of conceiving as if I try IVF?

We have all heard stories about friends coming back from a wine-soaked holiday to discover, to their astonishment, that they are pregnant. There’s a palpable sense of how did that happen? The reality is that, for most women struggling with fertility problems, this is the exception rather than the rule. However, research does suggest that taking care of what we put in our bodies may have a profound effect on upping our chances of getting a positive pregnancy test, even to the point of being as effective as IVF treatment.

In a review of the recent research, Dr Emma Derbyshire and her team from Manchester Metropolitan University revealed that in one study, while intrauterine insemination and ovarian stimulation gave a success rate of 33 per cent in conception, dietary advice was virtually as effective, leading to a 32 per cent success rate.

Read more: http://www.timesonline.co.uk/tol/life_and_style/health/expert_advice/article6787895.ece



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FertilityAuthority Expands its Online CommunityFertilityAuthority is taking the lead in the world of online fertility communities, adding three new blogs to their already impressive list of bloggers. The newest addition is “Holistic Fertility with Pulling Down the Moon,” a blog in which former fertility patients and Pulling Down the Moon co-founders Beth Heller and Tamara Quinn share a do-it-yourself approach to fertility which includes yoga, acupuncture, nutrition and massage.

The site has also added “Circle of Empty Arms,” created by author LaShaudra Seale who became a parent after adopting a son. Her blog focuses on reproductive technology options, the lack of healthcare for infertility treatments and adoption. “He Is Therefore I Am” now also appears on http://www.fertilityauthority.com/ . It is written by Tori Emmons who speaks about male factor infertility and her road to having a baby.

Read more: http://www.tribbleagency.com/?p=5563


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Beef up your zinc levels and give your fertility a boostIt is well known that shellfish is rich in zinc, the mineral essential for a host of bodily functions, from muscle-building to a healthy immune response. But did you know you can get your daily dose from a portion of beef steak?

'Lack of zinc is linked to wide-ranging health problems, including impaired immunity and fertility,' says Professor John Beattie, of the University of Aberdeen. 'It may even encourage the development of heart disease.'

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Older Women may soon be able to conceiveScientists have said that women might now be able to conceive at an age past child-bearing, all thanks to a new treatment that is expected to come up in the next ten years. Scientists have discovered a protein that they believe can be developed into a pill or even an injection to extend the life of the eggs in the ovary.

This could lead to a fertility revolution, as women would be able to wait longer to have a child.

Read more: http://www.healthjockey.com/2007/06/12/older-women-may-soon-be-able-to-conceive/


Scientists seem to have unlocked the key to human fertilityScientists at Leeds and Bradford have found a unique ‘DNA signature’ in human sperm, which may perhaps operate as a key that unlocks an egg’s fertility thereby stimulating new life.

Drs David Miller and David Iles from the University of Leeds, in partnership with Dr Martin Brinkworth at the University of Bradford, have discovered that sperm marks a DNA signature which could only be recognized by an egg from the same species. Apparently, this permits fertilization. Also, it may even elucidate how a species grows its own exclusive genetic identity.

Read more: http://www.healthjockey.com/2009/08/04/scientists-seem-to-have-unlocked-the-key-to-human-fertility/


More than a third of women have experienced fertility problemsMore than a third of women have experienced fertility problems, a new survey has found.

It also discovered that seven out of 10 childless women over the age of 30 worry about their fertility.

While delaying motherhood for a variety of reasons, women have it in "the back of their minds" they can try IVF [in vitro fertilization] if they fail to conceive naturally, the research for Red magazine found.

A total of 211 women had had successful fertility treatment or had decided they were not going to have any more, of which 124 had had IVF.

Read more: http://www.telegraph.co.uk/health/healthnews/5969134/More-than-a-third-of-women-have-experienced-fertility-problems.html


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